Since prazosin is more commonly used for high blood pressure, your doctor may want to look into its benefits for ptsd.
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When adding additional hypotensive agents or diuretics to prazosin therapy, decrease the dosage of prazosin to 1 to 2 mg po 3 times per day, then gradually increase as needed.
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Prazosin controls nightmares by crossing the blood-brain barrier and decreasing sympathetic outflow.
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analyses hierarchical linear modeling to test for main effects of prazosin mm versus placebo mm on alcohol use and ptsd symptoms over time, and to evaluate whether reductions in ptsd mediate the effect of prazosin.